In 1998, Cain started the Angry Dragon Entertainment production company, which produced the TBS Superstation television series Ripley's Believe It or Not! He has also starred in several films, including The Broken Hearts Club (2000), Out of Time (2003) and Bailey's Billion$ (2004). In 2004, he portrayed Scott Peterson in the made-for-television movie The Perfect Husband: The Laci Peterson Story. He appeared in a recurring role as Casey Manning in the television series Las Vegas. Cain made a return to the Superman franchise, with a special guest role in a season seven episode of Smallville as the immortal Dr. Curtis Knox, a character based upon the DC Comics villain Vandal Savage; and again in a recurring role on Supergirl, as the title character's foster father, Jeremiah Danvers. He is also the star of the VH1 hit series Hit the Floor as Pete Davenport, who is the new head coach of a fictional NBA team and has an illegitimate daughter who is a cheerleader for his NBA team. He was ranked No. 33 on VH1's 40 Hottest Hotties of the '90s.